bulletAim and Scopes

            

               

            

    

bulletTopics
bulletOrganizers
bulletProgramme
bulletLocation
bulletInvited Lectures
bulletExhibitors
bulletSpecial Session
bulletHotels
bulletToulouse Attractions / Excursions
bulletPublication Schedule
bullet Abstract Submission
bulletDraft Paper Submission
bulletInformation for presenting authors
bulletRegistration
bulletReview Process and Associated Journals
bulletTravel Information
bulletProceedings
bulletPhotos from the Conference
bulletContact

 

This website will be regularly updated with detailed information.

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Aim and Scopes

The Microfluidics 2010 Conference (µFlu’10) is the second European Conference in Microfluidics. It succeeds to µFlu’08 which was held in Bologna in December 2008. The aim of this conference is to strengthen the links inside the European scientific community in this young discipline and to promote exchanges between European Universities and Industrial Companies engaged in this field. Microfluidics finds applications in every industrial sector, as well as in numerous media covered fields like biology, medicine, chemical and process engineering, transports, environmental sciences, microelectronics and so on. The aim of this Conference is to promote and foster European cooperation in the field of Microfluidics by bringing together scientists and engineers working in this strongly multi-disciplinary area. The Conference invites submission of abstracts describing original works on the listed topics. The papers have to contain information on research rationale, methodology, results and major conclusions. Applied papers from Industries engaged in Microfluidics especially addressed to draw strong scientific needs are welcomed.

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Topics of the Conference

  1. Convective Micro Heat Transfer   (Co-chairs Tassos KARAYIANNIS & Denis MAILLET)

  2. Electrokinetic Microflows   (Co-chairs Carolyn REN & Sedat TARDU)

  3. Fluidic Microactuators and Micromixing   (Co-chairs Janko Auerswald & Ibrahim HASSAN)

  4. Gas Microflows   (Co-chairs Dimitris VALOUGEORGIS & Yonghao ZHANG)

  5. Lab on a Chip and Miniaturized Chemistry   (Co-chairs Panagiota ANGELI & Andrew DEMELLO)

  6. Liquid Microflows   (Co-chairs Juergen BRANDNER & Arjan FRIJNS)

  7. Microdroplets Management   (Co-chairs Yves FOUILLET & Marco Marengo)

  8. Microfabrication Techniques for Microfluidic Systems   (Co-chairs Anne-Marie GUé & Norbert KOCKMANN)

  9. Microflows in Bioengineering and Biofluidics   (Co-chairs David NEWPORT & Dimos POULIKAKOS)

  10. Microflow Visualisation and Measurements   (Co-chairs Lucien BALDAS & Ralph LINDKEN)

  11. Two-Phase Flows in Microsystems   (Co-chairs Gian Piero CELATA & Peter STEPHAN)

  12. Special Session: Cilia-Driven Flows   (Co chairs Jaap DEN TOONDER & Patrick ONCK)

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Special Session: Cilia-Driven Flows

Cilia and flagella are active microscopic hairs that cover the surface of some micro-organisms. The collective beating of cilia propels the micro-organism through a liquid. Hence the beating cilia induce a flow, which can be very effective: some cilia-propelled micro-organisms can swim about ten times their own length per second. Cilia driven flows can be found in numerous other places in nature, for example in humans: the Fallopian tube of females is covered with cilia that move the fertilized ovum from the ovary to the uterus, while motile cilia are also present in the lining of human lungs and the windpipe (trachea), to sweep mucus and dirt out of the airways in order to avoid infections.

Two micro-organisms that use cilia for propulsion, (a) Paramecium, (b) Pleurobrachia; (c) schematic of the asymmetric beating of an individual cilium.

Inspired by the micro-fluidic effectiveness of the natural cilia, various research groups have been developing artificial cilia in recent years, using various approaches. The aim is to create pumping, mixing, or propulsion in micro-fluidic devices.

Four examples of recently developed artificial cilia: (a) electrostatic cilia (den Toonder et al., Lab Chip 2008, 533); (b) magnetic cilia (Pokroy et al., Advanced Materials 2007, 1); (c) magnetic cilia (Evans et al., Nanoletters 2007, 1428); (d) light-actuated cilia (van Oosten et al., Nature Materials 2000, 677).

This special session about cilia driven flow will address the following issues:

bulletModeling of cilia and flagella and the effects on fluid flow
bulletBiological and artificial cilia: biomimetics
bulletMaterials and processing for artificial cilia
bulletIntegration into devices and applications
bulletCharacterization of cilia and flow

We are happy to receive proposed contributions on any of these topics!

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Exhibitors

Companies in the field of microfluidics will exhibit their products, equipments or instruments. A list of exhibitors with description of their activities will be soon available.

Companies interested in an exhibition stand are invited to read information in the exhibitors' flyer.

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Review Process and Associated Journals

Submitted abstracts will be reviewed by the scientific committee, mainly for checking adequation with the topics of the conference.

Following abstract acceptance, the submission of a full-length paper is mandatory for final acceptance of the communication at the conference. Full-length draft papers will be peer reviewed by at least 2 referees.

Two kinds of full-length paper will be accepted:

  1. Short papers (4-6 pages)
  2. Long papers (8-12 pages)

Both kinds of papers should include significant new scientific data.

All the accepted papers -without distinction between short and long papers- will be published in the CD-ROM Conference Proceedings, and after the conference a selection of the best long papers (8 pages and more) will be proposed by the scientific committee for publication in international journals:

bullet Microfluidics and Nanofluidics
bullet Biomicrofluidics (special issue)
bullet Experimental Heat Transfer
bullet International Journal of Microscale and Nanoscale Thermal and Fluid Transport Phenomena (special issue)
bullet Microsystem Technologies
bulletLa Houille Blanche - International Journal of Water

Only full-length papers accepted for the CD-ROM Conference Proceedings will be presented at the Conference.

Based on the comments of the referees, the accepted papers will be presented either as a long oral talk or as a short oral talk followed by discussion around a poster. This choice will be done by the scientific committee for a good balance of the sessions; the required scientific quality will be the same for oral and poster sessions.

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Publication Schedule

bulletSubmission of Abstract (the deadline has been extended)
bulletMay 22, 2010
late abstracts will be accepted after this deadline, provided the authors are able to submit the draft paper in respect with the deadline (August 15)
bulletAuthor Notification of Abstract Acceptance
bulletJune 5, 2010
bulletSubmission of Full-Length Draft Paper for Review (the deadline has been extended)
bulletAugust 15, 2010
bulletPaper Reviews Completed; Author Notification of Paper Acceptance
bulletOctober 6, 2010
bulletSubmission of Final Paper
bullet October 20, 2010
bulletDeadline for Early Bird Registration
bullet November 1, 2010
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Abstract Submission

Abstracts (between 200 and 1000 words) should be submitted online before May 22, 2010 (the deadline has been extended). They should only contain text, and provide detailed information on the objectives of the study, the methodology, the main results and major conclusions.

Abstract on-line submission is open.

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Draft paper submission

Once you have been informed that your abstract is accepted, you can prepare your full-length draft paper, following the appropriate paper-template provided in a Word or LaTex:

bullet Word 2003 template
bullet pdf template
bullet LaTeX template

Only full-length papers accepted for the CD-ROM Conference Proceedings will be presented at the Conference.

Full-length draft papers will be peer reviewed by at least 2 referees.

Two kinds of full-length paper will be accepted:

  1. Short papers (4-6 pages)
  2. Long papers (8-12 pages)

Both kinds of papers should include significant new scientific data.

After the review process, all the accepted papers -without distinction between short and long papers- will be published in the CD-ROM Conference Proceedings, and after the conference a selection of the best long papers (8 pages and more) will be proposed by the scientific committee for publication in international journals (see Review Process and Associated Journals)

Your draft must be submitted as a PDF file (A4 page format) with your paper number in the filename (e.g. MICROFLU2010-342.pdf),

On-line submission is now open.

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Registration

bulletRates, including proceedings on CDROM, lunches and banquet:
  Early Bird Rates
by November 10, 2010
Regular Rates
after November 10, 2010
  General € 500 € 550
  Students € 350 € 400

Online registration is now open.

For any further information about registration, please contact Brigitte Biton .

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Proceedings

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Programme

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Information for presenting authors

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Attractions / Excursions in and near Toulouse

For detailed information on Toulouse, see the guide for tourists and for an overview on Toulouse and its surroundings, visit the website of the great touristic sites in Midi-Pyrénées Region.

bulletToulouse, Heart of the South

At the heart of the Midi region, Toulouse has always occupied an important place in the South-West of France. This 2000-year-old history shows itself in an architecture of brick and tiles that is typical of the cities, villages and farms of the Midi-Pyrenees region. Reflections of the golden light on the brick of Toulouse have earned it the name of the ‘Ville Rose’. This very special colouring confers an atmosphere on the city that is at once gentle and warm.

Toulouse, France’s fourth biggest city, is bubbling over with life.There’s nothing like a stroll around the historic centre, walking alongside the Garonne and the Canal du Midi, or stopping in one of the many cafés whose terraces spill out onto the streets. All over the city, the ambience is friendly, tinged with the well-meaning familiarity that is particular to the people of Southern France. Toulouse is also a major shopping destination. All the main internationally-renowned brands in fashion, design, leather goods and jewellery are represented in Toulouse. The city neighbourhoods also live by the rhythm of the open-air and covered markets. Here you’ll find local products from the Midi-Pyrenees, which is one of the South-West’s most important gastronomic regions – producing wine, foie gras, cheeses, charcuterie, and of course cassoulet – the Toulousain dish par excellence.

bulletToulouse, at Nightfall

 

At nightfall, the city gets dressed up. A second, peaceful and nonchalant life begins as soon as the day’s work is over. Now is the time for relaxation – for the couples and families strolling amongst the young and seriously cool population of 100, 000 students.

The nightlife areas teem with life from cinemas, theatres and concert halls, to bars and restaurants – some of which also have shows and entertainment. Gourmets will appreciate the cosmopolitan cuisine available: local, foreign, simple, familial or gastronomic. In summer, the nights are warm and the nightlife can go on until the break of dawn.

A ‘Plan Lumière’ has recently highlighted sites and buildings with lighting specifically created for Toulouse: the Garonne, the churches, the façades, the pedestrian streets and the ‘places’ are shown off to their best advantage, offering a new vision of the urban landscape.

 

bulletToulouse, Time and History

2,000 years of Toulousain history have left the city scattered with a first-rate heritage that is representative of the Southern French style at various moments in history. The Saint-Sernin basilica, a jewel of 11th and 12th century Roman art, is an important stage on the Saint-Jacques-de-Compostelle pilgrimage. It is home to the grave of Saint Saturnin, first bishop of Toulouse in the 3rd century. The Jacobins convent buildings are visited for their Southern-French gothic architecture including the amazing “palm-tree”, a pillar from which twenty-two branches stem. At the heart of the antique dealer’s quarter, the Saint Etienne cathedral bears witness to the evolution of several styles of sacred architecture. The city is also very rich in Renaissance townhouses: hôtel de Bernuy, hôtel d’Assézat, hôtel de Pierre… Not to forget the Capitole, currently the City Hall, with its magnificently decorated historic rooms and the immense ‘place’ with its Occitan cross. Sneaking a peek under a porch can sometimes reveal stunning gardens and façades. 19th century industrial buildings renovated as cultural venues prolong the tradition of brick – such as the Galerie du Château d’Eau, the Musée des Abattoirs or the Bazacle – a permanent exhibition space on the banks of the Garonne.

bulletToulouse, Talents and Creation

Toulouse is a city to satisfy the taste of every enthusiast of the arts. A variety of concert halls stage performances of classical, lyrical art, jazz, variety and electro-acoustic music. Plays and café-theatre productions take place all year round – and a significant proportion of works are created by Toulousain companies. Dance and creative activities are supported by a very active and innovative choreographic centre. The great artistic collections housed in the museums and foundations of the city present works from Antiquity to the contemporary period: Roman statues, medieval art, fine arts, decorative arts, graphic arts, modern and contemporary art, photography – these permanent exhibitions are complemented by a policy of temporary exhibitions produced in Toulouse or in association with other national and international museums. Numerous art galleries also actively participate in the dynamic of artistic creation. Toulouse also stands out for its book culture: there are very well-stocked libraries, and a large mediatheque, as well as a great number of independent bookshops. Around fifteen festivals - music, theatre, humour, dance, visual arts, cinema, literature - are staged in the course of the year, and complete the cultural facilities that are already very eclectic.

bulletToulouse, Nature and Open Air

The Canal du Midi is the oldest canal in Europe, connecting the Atlantic to the Mediterranean.Toulouse is its central stopping point. With 382 locks, aqueducts and tunnels, it has earned Unesco’s ‘World Heritage Site’ label. The Garonne offers its banks and quays up to walkers and events, such as the ¡Río loco! festival in the month of June. Boat-trips and barges for hire allow you to experience the city from the water. With its many cycle tracks, not-very-hilly profile and short distances, Toulouse also lends itself to travel by bike. Bicycles can be rented for a few hours or by the day.Toulouse is dotted with green spaces and parks, from the simple oasis of calm in a neighbourhood with a historic park such as the Jardin des Plantes, whose 7 hectares are connected to the Jardin du Grand Rond and the Jardin Royal (both in the ‘English Romantic’ style). Not to be missed : the Prairie des Filtres, which offers the fresh air of the Garonne riverbanks, the japonese Compans-Cafarrelli garden, the Jardin Raymond VI, – a lively spot to pass through near the Musée des Abattoirs, and the new Museum gardens, an exceptionally well preserved natural environment in an urban setting. On the edges of the city, six leisure bases and seven golf courses complete the palette of local green spaces. The Toulousain identity on the green is rugby. This sport is emblematic of South-Western France and is a passion that beats in every Toulousain heart – proud of their team, the Toulouse Stadium and their multiple victories.

bulletToulouse, the Wings of Knowledge

Toulouse has been a land of aeronautical research for more than a century now. At the end of the 19th century, Clément Ader succeeded in making the strange machine he called an ‘avion’ take off. It was also from Toulouse that the first ‘Aéropostale’ airmail links were opened – an adventure that was immortalized in the writing of Antoine de Saint-Exupéry. The advent of the Airbus A380 today confirms Toulouse’s position as aeronautical capital. Research, innovation and industry are able to offer original opportunities to visit, for example, the Airbus assembly line or the Jolimont Observatoire. The Cité de l’Espace is a one-of-a-kind theme park covering 3.5 hectares. It offers a wide range of interactive activities which allow the visitor to understand the science of the earth and the cosmos, from the infinitesimally small to the infinitely big.

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Travel Information

Information about visa for France can be found on France Diplomatie Website.

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Hotels

For hotel reservation, you can directly book online with our partner
bullet in English
bullet in French
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Conference Co-Chairs

bulletStéphane COLIN, Université de Toulouse, France
bulletGian Luca MORINI, Universita di Bologna, Italy

Scientific Committee

bulletPanagiota ANGELI, University College London, UK
bulletJanko Auerswald, CSEM Alpnach, Switzerland
bulletLucien BALDAS, Université de Toulouse, France
bulletJuergen Brandner, Karlsruhe Institute of Technology, Germany
bulletGian Piero Celata, ENEA Rome, Italy
bulletAndrew DEMELLO, Imperial College London, UK
bulletJaap DEN TOONDER, Philips Applied Technologies, Eindhoven, The Netherlands
bulletYves Fouillet, CEA Grenoble, France
bulletArjan FRIJNS, Technische Universiteit Eindhoven, The Netherlands
bulletAnne-Marie Gué, LAAS-CNRS Toulouse, France
bulletIbrahim Hassan, Concordia University, Montreal, Canada
bulletTassos KARAYIANNIS, Brunel University, UK
bulletNorbert Kockmann, Lonza Ltd., Switzerland
bulletRalph Lindken, Centre for Fuel Cell Technology ZBT, Duisburg, Germany
bulletDenis MAILLET, Institut National Polytechnique de Nancy, France
bulletMarco Marengo, University of Bergamo, Italy
bulletDavid Newport, University of Limerick, Ireland
bulletPatrick ONCK, University of Groningen, The Netherlands
bulletDimos Poulikakos, ETH Zurich, Switzerland
bulletCarolyn REN, University of Waterloo, Canada
bulletPeter STEPHAN, Technische Universität Darmstadt, Darmstadt, Germany
bulletSedat Tardu, Institut National Polytechnique de Grenoble, France
bulletDimitris Valougeorgis, University of Thessaly, Greece
bulletYonghao Zhang, University of Strathclyde, Glasgow, UK

Organising Committee

bulletChristine BARROT, Université de Toulouse ICA
bulletBrigitte BITON, SHF
bulletHélène CHAUMAT, Université de Toulouse, LGC
bulletPaul DURU, Université de Toulouse, IMFT
bulletSandrine GEOFFROY, Université de Toulouse, ICA
bulletWafa GHOZLANI, Université de Toulouse, ICA-IMFT
bulletPierre JOSEPH, Université de Toulouse, LAAS
bulletNicolas LAURIEN, Université de Toulouse, ICA
bulletPascal LAVIEILLE, Université de Toulouse, LAPLACE
bulletJean-Georges PHILIPPS, SHF
bulletCyril RENAULT, Université de Toulouse, ICA-LGC
bulletFeriel SAMOUDA, Université de Toulouse, ICA
bulletPhilippe SCHMITZ, Université de Toulouse, LISBP
bulletClaire TENDERO, Université de Toulouse, CIRIMAT
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Location

bulletThe conference is hosted at the Meteo-France International Conference Center.

bulletWednesday evening: Welcome Reception hosted by the Major at the City Hall "Le Capitole".

bulletThursday evening: Banquet at "La Médiathèque"

You can see the location of the conference, the banquet, the welcome reception and the main proposed hotels on the map below.
We recommand you to book an hotel in the town center (see Hotel Section). The access to the Meteo-France International Conference Center is easy and rapid by metro (details about metro line will be added soon). These hotels are close to "La médiathèque" and "Le Capitole".


You can display µFlu'2010 on a wider map.
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Invited lectures

Each half-day of the conference begins with an invited lecture.

bulletOptimization of convective heat transfer in micro scale applications, presented by Martine BAELMANS, Department of Mechanical Engineering, Katholieke Universiteit Leuven, Belgium.
bulletAbstract   
Selected state of the art microscale convective heat transfer techniques are presented for use in heat sinks and heat exchangers. Hereby focus is put on optimal design aspects. For direct liquid cooled heat sink applications, steady and unsteady single-phase flow operation are discussed and compared with possible operating conditions for two-phase flow. Regarding compact heat exchanger applications, the effects of downscaling are discussed in terms of the penalties on hydraulic and thermal performance. Comparing the optimal design of heat sinks (minimal thermal resistance and gradients) and heat exchangers (maximal power density), different criteria for flow conditions and material properties emerge
.
bulletBiography

 Prof. Martine BAELMANS

Martine Baelmans is Professor at the Department of Mechanical Engineering at the Katholieke Universiteit Leuven in Belgium. She graduated from the Katholieke Universiteit Leuven and obtained her Ph.D. in Engineering in 1993.

Within the division Applied Mechanics and Energy Conversions professor Martine Baelmans leads the group on thermal-fluid engineering. Research topics range from fundamental turbulence research to application oriented thermal design in telecom systems, power electronics and power transformers. She has authored or co-authored more than 150 papers in applications on fluid mechanics and heat transfer.

 

bulletAcoustically Activated Microfluidic Manipulations, presented by Jon COOPER, Department of Electronics, University of Glasgow, UK.
bulletAbstract   
The development of microfluidic systems is often constrained both by difficulties associated with the chip interconnection to other instruments and by mechanisms that can enable fluid movement and processing. Surface acoustic wave (SAW) devices have previously shown promise in allowing samples to be manipulated, although designing complex fluid manipulations involves mixed signal generation at multiple electrode transducers. We now demonstrate a simple interface between a piezoelectric SAW device and a disposable microfluidic chip, patterned with phononic structures to shape the acoustic field. The surface wave is coupled from the piezoelectric substrate into the disposable chip where it interacts with the phononic lattice. This allows fluid actuations, including droplet movement, splitting, jetting, nebulisation and centrifugation to be performed.  We show that the interaction of the fluid within the phononic structure is dependent upon the frequency of the acoustic wave, providing a method to programme complex fluidic functions into a microchip.
bulletBiography

 Prof. Jon COOPER

Professor Jon Cooper holds the Wolfson Chair in Bioengineering. He has developed a range of technologies associated with Lab-on-a-Chip for diagnostics, cell measurements and proteomics. The primary focus of his work has been the demonstration of the analytical advantages of studying bioloigical systems at the micro- and nanoscale. He has strong collaborations with the Beatson (in cell based arrays for cancer research) and with the BHF (in developing new tools for drug discovery in heart disease). He is a founder of the chip based diagnostic devices for the detection of bowel cancer (www.modedx.com).

Professor Cooper was elected as a Fellow of the Royal Society of Edinburgh in 2001 and a Fellow of the Royal Academy of Engineering in 2004. Professor Cooper's work is recognised by invited lectures at leading conferences. He has published ca. 175 papers in the field.

 

bulletGPU Accelerated Simulations of Rarefied Gases Microflows, presented by Aldo FREZZOTTI, Dipartimento di Matematica del Politecnico di Milano, Italy.
bulletAbstract   
The advent of high level programming tools[1] has made the huge number crunching capabilities of modern graphic processing units (GPU's) available for scientific simulations. The benefits of this new computing platform are particularly evident in the numerical solution of kinetic equations used to investigate the properties of those gaseous microflows in which rarefaction effects cannot be neglected. As a matter of fact, the evaluation or simulation of collision terms, which absorbs most of the computational resources in rarefied gas flow simulations, can be concurrently performed due to their local structure. Recent results have shown that the computing time of both deterministic kinetic model equations simulations and semi-deterministic simulations based on the full Boltzmann equation can be reduced of two orders of magnitude by porting sequential codes on GPU's. Starting from the obtained results, it will be shown that, although the traditional Direct Simulation Monte Carlo is not well suited to the SIMD structure of GPU's, it is possible to reformulate the scheme in order to obtain considerable speedups.
bulletBiography

 Prof. Aldo FREZZOTTI

Aldo Frezzotti graduated cum laude in theoretical physics in the University of Milano in 1977. In 1978 he obtained a reasearch fellowship from Euratom and joined a group in the European Institute for Transuranium Elements in Karlsruhe (Germany) to study gas dynamics of laser induced evaporation and the equation of state of advanced nuclear fuels. From 1981 to 1983 he was the head of a research group in the Research and Development Center of Alfa Romeo in Milano, whose main activity was devoted to developing codes for simulating combustion phenomena in automotive engines.
In 1984 he obtained a position as Assistant Professor in Politecnico di Milano where he became Full Professor in 2000. Prof. Frezzotti's reserch activity is mainly devoted to the applications and numerical aspects of kinetic theory of rarefied and dense fluids.
 

 

bulletExpanding the Scope of Isotachophoresis in Microfluidic Operations, presented by Steffen HARDT, Institute for Nano- and Microfluidics, Center of Smart Interfaces, TU Darmstadt, Germany.
bulletAbstract   
Isotachophoresis (ITP) is a version of electrophoresis utilizing at least two different electrolytes, a leading electrolyte (LE) and a terminating electrolyte (TE). At the LE/TE interface molecules may be focused and separated according to their electrophoretic mobility. Along these lines, ITP has been used in analytical chemistry for sample preconcentration and separation. We show that the scope of ITP may be expanded beyond such “traditional” applications and demonstrate that it may as well be utilized for bringing minute samples into contact and performing particle separations.
A key operation in combinatorial chemistry is to perform and screen reactions between samples. In that context it is desirable to handle very small sample amounts while maintaining a high concentration. ITP is ideally suited for that purpose. We demonstrate a microfluidic device allowing the handling of picoliter samples that can be brought into contact in a well controlled manner. Furthermore, we show how ITP may be utilized to perform particle separations. Microparticles introduced into the LE may be carried along with the LE/TE interface, depending on their properties. Based on that principle we have been able to perform a size separation of different particles. In contrast to existing approaches such as dielectrophoretic separation, this technique does not require any electrodes or sophisticated microstructures. The experimental efforts in developing novel ITP-based microfluidic schemes are supported by modeling and simulation efforts, especially targeting the interplay between ITP and electroosmotic flow. The presented examples suggest that ITP bears a potential going well beyond the usual analytical applications and may be utilized for a number of different microfluidic operations, many of which may still be unexplored.
bulletBiography

 Prof. Steffen HARDT

 Steffen Hardt studied physics at the University of Giessen and the University of Washington/Seattle and obtained his Ph.D. in Giessen in the area of theoretical particle physics. After that he joined the Institute of Microtechnology Mainz where he shifted his research focus to microfluidics and worked in application-oriented r&d projects. After spending some time at the Chair of Technical Thermodynamics at TU Darmstadt he accepted an appointment at the University of Hannover where he headed the Institute for Nano- and Micro Process Technology. Since April 2009 he has been working at the Center of Smart Interfaces at TU Darmstadt where he serves as head of the Institute for Nano- and Microfluidics. His research interests include nano- and microfluidics, optofluidics, heat and mass transfer processes, electrokinetics, fluidic phase boundaries, lab-on-a-chip technology, and energy conversion processes.

 

bulletThe River Within: Cilia Forces, Mucus Physics and Biomimetic Arrays to Understand Mucus Clearance, presented by Richard SUPERFINE, Department of Physics and Astronomy, University of North Carolina at Chapel Hill, NC, USA.
bulletAbstract   
The lung maintains an air/blood interface with a surface area the size of half a tennis court. This huge surface area presents a challenge to physiology to maintain a sterile environment in the presence of continual assaults from inhaled environmental pathogens. The body is successful by secreting a layer of mucus, a viscoelastic polymeric fluid, onto the epithelial surface to trap dust and unwanted visitors. This mucus filter is then changed through the continual upward flow due to beating cilia and cough. We are attempting to understand each aspect of this process through biophysical measurements and through the development of engineered biomimetic systems. Using a magnetic microbead assay, we have measured the force developed by individual lung cilia. To understand the response of the mucus, we measure the fluid rheology using driven microbead rheology that reveals the strain thickening behavior due to high shear rates at the surface of micro and nano sized structures. Finally, to understand the flows generated by carpets of cilia, we have engineered artificial cilia at the size scale of their biological counterparts and have observed directed flow and enhanced mixing in actuated arrays.
bulletBiography

 Prof. Richard SUPERFINE

Richard Superfine, Taylor-Williams Distinguished Professor of Physics and Astronomy at the University of North Carolina at Chapel Hill, received his B. S. in physics from Lehigh University and worked at AT&T Bell Laboratories for three years before moving to University of California, Berkeley to obtain his Physics Ph.D. in laser studies of molecular surfaces. Since arriving at UNC Chapel Hill, his research includes the study of nanoscale phenomena in nanodevices, biological forces, biofluids and the systems biology of lung defense. He is the principal investigator of the UNC NIH resource for Computer Integrated Systems for Manipulation and Microscopy (CISMM.org) which develops tools for biomedical sciences. One microscopy system, the nanoManipulator, has been commercialized and has won an R&D 100 award (2001). He has received the Macres Award from the Microbeam Analytical Society, the Hettelman Prize for excellence in scholarship from UNC-CH, and for distinguished undergraduate teaching at UNC-CH , the Johnson Award and the Bowman and Gordon Gray Professorship. He is principal investigator of the Virtual Lung Project which brings together biophysical and biochemical measurements of mucus clearance together with computational modeling to create an integrated, predictive model for lung defense.

 

bulletProgress in Droplet-Based Microfluidics, presented by Patrick TABELING, École Supérieure de Physique et de Chimie Industrielle, Paris, France.
bulletAbstract   
Developing biochemical and chemical processes in microdroplets rather than in microchannels or microchambers is an idea that has been promoted over the last few years by several groups. Among the main advantages of microdroplet approach, one may mention the absence of contact between the chemical species and the walls, the possibility of varying, in each droplet, the physico-chemical conditions under which chemical or biochemical processes develop (opening the way to screening), and the fast mixing that takes place in each droplet. This approach naturally leads to envision microfluidic systems with mazes of microchannels along which droplets conveying solutes, materials, particles, undergo transformations, reactions and processes. We are still far from this stage, but progress reported recently in the literature point in that direction. I will describe the experimental effort we developed in this domain, over the last couple of years, in the Microfluidic Group of ESPCI. The talk will focus on droplet breakup in simple microfluidic geometries, generation of colloidal droplets, expression profiling at the single cell level (using droplet based microfluidics) and localized drug delivery using micrometric droplets as vectors.
bulletBiography

 Prof. Patrick TABELING

Patrick Tabeling is Directeur de Recherches CNRS and Professor ESPCI. He is graduated from ESE and obtained his PhD in 1976, followed by the these d'Etat in 1980. He has been working in the domain of physical hydrodynamics at ENS from 1984 to 2000. He moved to ESPCI in 2001 and is now working in the domain of Microfluidics, at ESCPI, where he is responsible of the Microfluidic Lab.

His interests include the fundamental processes occuring in microfluidic systems and the applications of microfluidic technology to a variety of fields. He is author of 150 papers and 7 patents.

 

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Photos from the Conference

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Contact

For further information, please contact us.

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For any inquiries or problems regarding this Web page, please contact the webmaster.
Last modification : 08/27/2010.